Poorly differentiated small cell carcinoma of the pancreas: a case report and review of the literature

Small cell carcinoma (SCC) of the pancreas is a rare malignancy with an extremely poor prognosis. We present the case of a 74-year-old man with a 2-month history of upper abdominal discomfort who was diagnosed with SCC of the pancreas tail, involvement of peri-pancreatic and mesenteric lymph nodes a...

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Hauptverfasser: Berkel, Simone (VerfasserIn) , Hummel, Frank (VerfasserIn) , Gaa, Jochen (VerfasserIn) , Back, Walter (VerfasserIn) , Hofheinz, Ralf-Dieter (VerfasserIn) , Queißer, Wolfgang (VerfasserIn) , Singer, Manfred V. (VerfasserIn) , Löhr, J.-Matthias (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: August 27, 2004
In: Pancreatology
Year: 2004, Jahrgang: 4, Heft: 6, Pages: 521-526
ISSN:1424-3911
DOI:10.1159/000080526
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1159/000080526
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1424390304800383
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Verfasserangaben:Simone Berkel, Frank Hummel, Jochen Gaa, Walter Back, Ralf Hofheinz, Wolfgang Queisser, Manfred V. Singer, Matthias Löhr
Beschreibung
Zusammenfassung:Small cell carcinoma (SCC) of the pancreas is a rare malignancy with an extremely poor prognosis. We present the case of a 74-year-old man with a 2-month history of upper abdominal discomfort who was diagnosed with SCC of the pancreas tail, involvement of peri-pancreatic and mesenteric lymph nodes and multiple liver metastases (extended disease). A CT scan and a positive somatostatin receptor scintigraphy showed no evidence of a primary lung tumour. The diagnosis of a SCC was confirmed by biopsy. Local tumour control could be achieved by gemcitabine once a week and a long-acting somatostatin analogue once a month, but liver metastasis showed progress. Thus, 5-fluorouracil on a weekly basis was started. The patient died 8 months after diagnosis and had not been hospitalised in the meantime.
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Beschreibung:Online Resource
ISSN:1424-3911
DOI:10.1159/000080526