Matrix metalloproteinases in cerebrovascular diseases
Matrix metalloproteinases are important factors for tissue remodelling and are activated during several physiological and pathological conditions, including cerebrovascular diseases. We give an overview of the structure, production and physiological effects of these widely distributed proteases and...
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
July 27, 2005
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| In: |
Cerebrovascular diseases
Year: 2005, Volume: 20, Issue: 3, Pages: 141-151 |
| ISSN: | 1421-9786 |
| DOI: | 10.1159/000087197 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1159/000087197
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| Author Notes: | Marc Fatar, Mark Stroick, Martin Griebe, Michael Hennerici |
| Summary: | Matrix metalloproteinases are important factors for tissue remodelling and are activated during several physiological and pathological conditions, including cerebrovascular diseases. We give an overview of the structure, production and physiological effects of these widely distributed proteases and describe the genetic background and regulation pathways. In particular, we discuss the role of matrix metalloproteinases in vascular remodelling concerning ischaemic stroke, brain haemorrhage, vascular dementia, carotid artery plaques and cerebral aneurysms. |
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| Item Description: | Gesehen am 10.05.2022 |
| Physical Description: | Online Resource |
| ISSN: | 1421-9786 |
| DOI: | 10.1159/000087197 |