The FDA-approved drug cobicistat synergizes with remdesivir to inhibit SARS-CoV-2 replication in vitro and decreases viral titers and disease progression in Syrian hamsters

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Main Authors: Shytaj, Iart Luca (Author) , Fares, Mohamed (Author) , Gallucci, Lara (Author) , Lucic, Bojana (Author) , Tolba, Mahmoud M. (Author) , Zimmermann, Liv (Author) , Adler, Julia M. (Author) , Xing, Na (Author) , Bushe, Judith (Author) , Gruber, Achim D. (Author) , Ambiel, Ina (Author) , Taha Ayoub, Ahmed (Author) , Cortese, Mirko (Author) , Neufeldt, Christopher (Author) , Stolp-Rastätter, Bettina (Author) , Sobhy, Mohamed Hossam (Author) , Fathy, Moustafa (Author) , Zhao, Min (Author) , Laketa, Vibor (Author) , Diaz, Ricardo Sobhie (Author) , Sutton, Richard E. (Author) , Chlanda, Petr (Author) , Boulant, Steeve (Author) , Bartenschlager, Ralf (Author) , Stanifer, Megan (Author) , Fackler, Oliver Till (Author) , Trimpert, Jakob (Author) , Savarino, Andrea (Author) , Lusic, Marina (Author)
Format: Article (Journal)
Language:English
Published: 1 March 2022
In: mBio
Year: 2022, Volume: 13, Issue: 2, Pages: 1-23
ISSN:2150-7511
DOI:10.1128/mbio.03705-21
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1128/mbio.03705-21
Verlag, lizenzpflichtig, Volltext: https://journals.asm.org/doi/10.1128/mbio.03705-21
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Author Notes:Iart Luca Shytaj, Mohamed Fares, Lara Gallucci, Bojana Lucic, Mahmoud M. Tolba, Liv Zimmermann, Julia M. Adler, Na Xing, Judith Bushe, Achim D. Gruber, Ina Ambiel, Ahmed Taha Ayoub, Mirko Cortese, Christopher J. Neufeldt, Bettina Stolp, Mohamed Hossam Sobhy, Moustafa Fathy, Min Zhao, Vibor Laketa, Ricardo Sobhie Diaz, Richard E. Sutton, Petr Chlanda, Steeve Boulant, Ralf Bartenschlager, Megan L. Stanifer, Oliver T. Fackler, Jakob Trimpert, Andrea Savarino, Marina Lusic
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Item Description:Gesehen am 31.05.2022
Physical Description:Online Resource
ISSN:2150-7511
DOI:10.1128/mbio.03705-21