Biodegradation of absorbable sutures in body fluids and pH buffers
Objective: This study measures the influence of body fluids on the loss of tensile strength of absorbable sutures in vitro. Methods: Nine synthetic absorbable sutures were incubated in different gastrointestinal fluids, as well as in blood and three buffers. Stretch tests were performed after days 0...
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| Main Authors: | , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2004
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| In: |
European surgical research
Year: 2004, Volume: 36, Issue: 6, Pages: 376-385 |
| ISSN: | 1421-9921 |
| DOI: | 10.1159/000081648 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1159/000081648 Verlag, lizenzpflichtig, Volltext: https://www.karger.com/Article/FullText/81648 
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| Author Notes: | S. Freudenberg, S. Rewerk, M. Kaess, Christel Weiss, A. Dorn-Beinecke, S. Post |
| Summary: | Objective: This study measures the influence of body fluids on the loss of tensile strength of absorbable sutures in vitro. Methods: Nine synthetic absorbable sutures were incubated in different gastrointestinal fluids, as well as in blood and three buffers. Stretch tests were performed after days 0, 7, 14, and 21. Results: Tensile strength varied from 18.5 to 32.8 N, and elasticity varied from 9.5 to 51% of the initial length. The influence of pH, blood, and gastric juice was negligible on all sutures except PDS II®. Except for Monocryl®, all sutures, especially Polysorb® and Vicryl®, lost tensile strength much faster in bile, jejunal and pancreatic juices than in the corresponding buffers. Conclusion: The biodegradation of sutures varies greatly in different body fluids independent of differences in pH. |
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| Item Description: | Gesehen am 31.05.2022 |
| Physical Description: | Online Resource |
| ISSN: | 1421-9921 |
| DOI: | 10.1159/000081648 |