Neoadjuvant irradiation of extremity soft tissue sarcoma with ions (Extrem-ion): study protocol for a randomized phase II pilot trial

The standard of care treatment for soft tissue sarcoma of the extremities is a wide resection in combination with pre- or postoperative radiotherapy with high local control rates, sparing patients the necessity of amputation without compromising on overall survival rates.

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Main Authors: Brügemann, Dirk (Author) , Lehner, Burkhard (Author) , Kieser, Meinhard (Author) , Krisam, Johannes (Author) , Hommertgen, Adriane (Author) , Jäkel, Cornelia (Author) , Harrabi, Semi B. (Author) , Herfarth, Klaus (Author) , Mechtersheimer, Gunhild (Author) , Sedlaczek, Oliver (Author) , Egerer, Gerlinde (Author) , Geisbüsch, Andreas (Author) , Uhl, Matthias (Author) , Debus, Jürgen (Author) , Seidensaal, Katharina (Author)
Format: Article (Journal)
Language:English
Published: 12 May 2022
In: BMC cancer
Year: 2022, Volume: 22, Pages: 1-8
ISSN:1471-2407
DOI:10.1186/s12885-022-09560-x
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12885-022-09560-x
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Author Notes:D. Brügemann, B. Lehner, M. Kieser, J. Krisam, A. Hommertgen, C. Jaekel, S. B. Harrabi, K. Herfarth, G. Mechtesheimer, O. Sedlaczek, G. Egerer, A. Geisbüsch, M. Uhl, J. Debus and K. Seidensaal
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Summary:The standard of care treatment for soft tissue sarcoma of the extremities is a wide resection in combination with pre- or postoperative radiotherapy with high local control rates, sparing patients the necessity of amputation without compromising on overall survival rates.
Item Description:Gesehen am 24.06.2022
Physical Description:Online Resource
ISSN:1471-2407
DOI:10.1186/s12885-022-09560-x