Using matrix-assisted laser desorption ionization-time of flight mass spectrometry to detect carbapenem resistance within 1 to 2.5 hours
In recent years, the percentage of carbapenem-resistant bacteria has increased at an alarming pace and become a major threat for patient survival. Carbapenemase-induced carbapenem resistance can be confirmed through the detection of carbapenem degradation using matrix-assisted laser desorption ioniz...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
September 2011
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| In: |
Journal of clinical microbiology
Year: 2011, Volume: 49, Issue: 9, Pages: 3321-3324 |
| ISSN: | 1098-660X |
| DOI: | 10.1128/JCM.00287-11 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1128/JCM.00287-11 Verlag, lizenzpflichtig, Volltext: https://journals.asm.org/doi/10.1128/JCM.00287-11 
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| Author Notes: | Irene Burckhardt and Stefan Zimmermann |
| Summary: | In recent years, the percentage of carbapenem-resistant bacteria has increased at an alarming pace and become a major threat for patient survival. Carbapenemase-induced carbapenem resistance can be confirmed through the detection of carbapenem degradation using matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). This method works for strains carrying NDM-1, VIM-1, VIM-2, KPC-2, and different IMP enzymes. |
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| Item Description: | Gesehen am 24.06.2022 |
| Physical Description: | Online Resource |
| ISSN: | 1098-660X |
| DOI: | 10.1128/JCM.00287-11 |