A common evolutionary origin reveals fundamental principles of protein insertases
Membrane proteins require protein machineries to insert their hydrophobic transmembrane domains (TMDs) into the lipid bilayer. A functional analysis of protein insertases in this issue of PLOS Biology reveals that the fundamental mechanism of membrane protein insertion is universally conserved.
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
March 2, 2022
|
| In: |
PLoS biology
Year: 2022, Volume: 20, Issue: 3, Pages: 1-4 |
| ISSN: | 1545-7885 |
| DOI: | 10.1371/journal.pbio.3001558 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1371/journal.pbio.3001558 Verlag, lizenzpflichtig, Volltext: https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001558 
|
| Author Notes: | F.-Nora Vögtle, Hans-Georg Koch, Chris Meisinger |
| Summary: | Membrane proteins require protein machineries to insert their hydrophobic transmembrane domains (TMDs) into the lipid bilayer. A functional analysis of protein insertases in this issue of PLOS Biology reveals that the fundamental mechanism of membrane protein insertion is universally conserved. |
|---|---|
| Item Description: | Gesehen am 28.06.2022 |
| Physical Description: | Online Resource |
| ISSN: | 1545-7885 |
| DOI: | 10.1371/journal.pbio.3001558 |