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The future of adhesion prophylaxis trials in abdominal surgery: an expert global consensus

Postoperative adhesions represent a frequent complication of abdominal surgery. Adhesions can result from infection, ischemia, and foreign body reaction, but commonly develop after any surgical procedure. The morbidity caused by adhesions affects quality of life and, therefore, it is paramount to co...

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Main Authors: Wilde, Rudy Leon de (Author) , Devassy, Rajesh (Author) , Broek, Richard P. G. ten (Author) , Miller, Charles E. (Author) , Adlan, Aizura (Author) , Aquino, Prudence (Author) , Becker, Sven (Author) , Darmawan, Ferry (Author) , Gergolet, Marco (Author) , Habana, Maria Antonia E. (Author) , Khoo, Chong Kiat (Author) , Koninckx, Philippe R. (Author) , Korell, Matthias (Author) , Krentel, Harald (Author) , Musigavong, Olarik (Author) , Pistofidis, George (Author) , Puntambekar, Shailesh (Author) , Rachman, Ichnandy A. (Author) , Sendag, Fatih (Author) , Wallwiener, Markus (Author) , Torres-de la Roche, Luz Angela (Author)
Format: Article (Journal)
Language:English
Published: 8 March 2022
In: Journal of Clinical Medicine
Year: 2022, Volume: 11, Issue: 6, Pages: 1-9
ISSN:2077-0383
DOI:10.3390/jcm11061476
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.3390/jcm11061476
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/2077-0383/11/6/1476
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Author Notes:Rudy Leon De Wilde, Rajesh Devassy, Richard P.G. ten Broek, Charles E. Miller, Aizura Adlan, Prudence Aquino, Sven Becker, Ferry Darmawan, Marco Gergolet, Maria Antonia E. Habana, Chong Kiat Khoo, Philippe R. Koninckx, Matthias Korell, Harald Krentel, Olarik Musigavong, George Pistofidis, Shailesh Puntambekar, Ichnandy A. Rachman, Fatih Sendag, Markus Wallwiener and Luz Angela Torres-de la Roche
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Summary:Postoperative adhesions represent a frequent complication of abdominal surgery. Adhesions can result from infection, ischemia, and foreign body reaction, but commonly develop after any surgical procedure. The morbidity caused by adhesions affects quality of life and, therefore, it is paramount to continue to raise awareness and scientific recognition of the burden of adhesions in healthcare and clinical research. This 2021 Global Expert Consensus Group worked together to produce consented statements to guide future clinical research trials and advise regulatory authorities. It is critical to harmonize the expectations of research, to both develop and bring to market improved anti-adhesion therapies, with the ultimate, shared goal of improved patient outcomes.
Item Description:Gesehen am 02.07.2022
This article belongs to the Special Issue "Challenges and Controversies in Minimally Invasive Surgery: What Is Really New in Gynecologic Surgery?"
Physical Description:Online Resource
ISSN:2077-0383
DOI:10.3390/jcm11061476

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