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Tolerance of biofilm of a carbapenem-resistant Klebsiella pneumoniae involved in a duodenoscopy-associated outbreak to the disinfectant used in reprocessing

One possible transmission route for nosocomial pathogens is contaminated medical devices. Formation of biofilms can exacerbate the problem. We report on a carbapenemase-producing Klebsiella pneumoniae that had caused an outbreak linked to contaminated duodenoscopes. To determine whether increased to...

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Bibliographic Details
Main Authors: Brunke, Melanie Sarah (Author) , Konrat, Katharina (Author) , Schaudinn, Christoph (Author) , Piening, Brar (Author) , Pfeifer, Yvonne (Author) , Becker, Laura (Author) , Schwebke, Ingeborg (Author) , Arvand, Mardjan (Author)
Format: Article (Journal)
Language:English
Published: 03 June 2022
In: Antimicrobial resistance and infection control
Year: 2022, Volume: 11, Pages: 1-7
ISSN:2047-2994
DOI:10.1186/s13756-022-01112-z
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13756-022-01112-z
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Author Notes:Melanie S. Brunke, Katharina Konrat, Christoph Schaudinn, Brar Piening, Yvonne Pfeifer, Laura Becker, Ingeborg Schwebke and Mardjan Arvand
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Summary:One possible transmission route for nosocomial pathogens is contaminated medical devices. Formation of biofilms can exacerbate the problem. We report on a carbapenemase-producing Klebsiella pneumoniae that had caused an outbreak linked to contaminated duodenoscopes. To determine whether increased tolerance to disinfectants may have contributed to the outbreak, we investigated the susceptibility of the outbreak strain to disinfectants commonly used for duodenoscope reprocessing. Disinfection efficacy was tested on planktonic bacteria and on biofilm.
Item Description:Gesehen am 06.07.2022
Physical Description:Online Resource
ISSN:2047-2994
DOI:10.1186/s13756-022-01112-z

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