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Alcohol: basic and translational research: 15th annual Charles Lieber &1st Samuel French satellite symposium

The present review is based on the research presented at the symposium dedicated to the legacy of the two scientists that made important discoveries in the field of alcohol-induced liver damage: Professors C.S. Lieber and S.W. French. The invited speakers described pharmacological, toxicological and...

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Main Authors: Neuman, Manuela G. (Author) , Seitz, Helmut K. (Author) , Tuma, Pamela L. (Author) , Osna, Natalia A. (Author) , Casey, Carol A. (Author) , Kharbanda, Kusum K. (Author) , Cohen, Lawrence B. (Author) , Malnick, Steve D. H. (Author) , Adhikari, Raghabendra (Author) , Mitra, Ramyajit (Author) , Dagur, Raghubendra Singh (Author) , Ganesan, Murali (Author) , Srinivas, Chava (Author) , Madan Kumar, Arumugam (Author) , New-Aaron, Moses (Author) , Poluektova, Larisa (Author) , Thomes, Paul G. (Author) , Rasineni, Karuna (Author) , Opris, Mihai (Author) , Teschke, Rolf (Author)
Format: Article (Journal) Conference Paper
Language:English
Published: 19 February 2022
In: Experimental and molecular pathology
Year: 2022, Volume: 126, Pages: 1-7
ISSN:1096-0945
DOI:10.1016/j.yexmp.2022.104750
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.yexmp.2022.104750
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0014480022000107
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Author Notes:Manuela G. Neuman, Helmut K. Seitz, Pamela L. Tuma, Natalia A. Osna, Carol A. Casey, Kusum K. Kharbanda, Lawrence B. Cohen, Steve D.H. Malnick, Raghabendra Adhikari, Ramyajit Mitra, Raghubendra Singh Dagur, Murali Ganesan, Chava Srinivas, Arumugam Madan Kumar, Moses New-Aaron, Larisa Poluektova, Paul G. Thomes, Karuna Rasineni, Mihai Opris, Rolf Teschke
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Summary:The present review is based on the research presented at the symposium dedicated to the legacy of the two scientists that made important discoveries in the field of alcohol-induced liver damage: Professors C.S. Lieber and S.W. French. The invited speakers described pharmacological, toxicological and patho-physiological effects of alcohol misuse. Moreover, genetic biomarkers determining adverse drug reactions due to interactions between therapeutics used for chronic or infectious diseases and alcohol exposure were discussed. The researchers presented their work in areas of alcohol-induced impairment in lipid protein trafficking and endocytosis, as well as the role of lipids in the development of fatty liver. The researchers showed that alcohol leads to covalent modifications that promote hepatic dysfunction and injury. We concluded that using new advanced techniques and research ideas leads to important discoveries in science.
Item Description:Gesehen am 21.07.2022
Physical Description:Online Resource
ISSN:1096-0945
DOI:10.1016/j.yexmp.2022.104750

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