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The interleukin-7 receptor α chain contributes to altered homeostasis of regulatory T cells in multiple sclerosis

Treg homeostasis is disturbed in multiple sclerosis (MS). Frequencies of recent thymic emigrant (RTE)-Treg are reduced and the disparity between RTE-Treg and long-lived memory Treg coincides with the MS-associated Treg defect, as shown previously.

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Bibliographic Details
Main Authors: Haas, Jürgen (Author) , Korporal-Kuhnke, Mirjam (Author) , Schwarz, Alexander (Author) , Balint, Bettina (Author) , Wildemann, Brigitte (Author)
Format: Article (Journal)
Language:English
Published: 2011
In: European journal of immunology
Year: 2011, Volume: 41, Issue: 3, Pages: 845-853
ISSN:1521-4141
DOI:10.1002/eji.201041139
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/eji.201041139
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/10.1002/eji.201041139
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Author Notes:Jürgen Haas, Mirjam Korporal, Alexander Schwarz, Bettina Balint and Brigitte Wildemann
Description
Summary:Treg homeostasis is disturbed in multiple sclerosis (MS). Frequencies of recent thymic emigrant (RTE)-Treg are reduced and the disparity between RTE-Treg and long-lived memory Treg coincides with the MS-associated Treg defect, as shown previously.
Item Description:First published: 09 December 2010
Gesehen am 25.07.2022
Physical Description:Online Resource
ISSN:1521-4141
DOI:10.1002/eji.201041139

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