Long-term effect of efavirenz autoinduction on plasma/peripheral blood mononuclear cell drug exposure and CD4 count is influenced by UGT2B7 and CYP2B6 genotypes among HIV patients
AbstractObjectives. We investigated the long-term effect of efavirenz autoinduction on its plasma/peripheral blood mononuclear cell (PBMC) exposure and the CD4 count, and the importance of sex and pharmacogenetic variations.
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
October 2011
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| In: |
The journal of antimicrobial chemotherapy
Year: 2011, Jahrgang: 66, Heft: 10, Pages: 2350-2361 |
| ISSN: | 1460-2091 |
| DOI: | 10.1093/jac/dkr304 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1093/jac/dkr304 Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/jac/article/66/10/2350/733406 |
| Verfasserangaben: | Abiy Habtewold, Wondwossen Amogne, Eyasu Makonnen, Getnet Yimer, Klaus-Dieter Riedel, Nobuhisa Ueda, Alemayehu Worku, Walter Emil Haefeli, Lars Lindquist, Getachew Aderaye, Jürgen Burhenne and Eleni Aklillu |
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| 520 | |a AbstractObjectives. We investigated the long-term effect of efavirenz autoinduction on its plasma/peripheral blood mononuclear cell (PBMC) exposure and the CD4 count, and the importance of sex and pharmacogenetic variations. | ||
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