Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity

Massively parallel sequencing technologies have brought an enormous increase in sequencing throughput. However, these technologies need to be further improved with regard to reproducibility and applicability to clinical samples and settings.

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Bibliographic Details
Main Authors: Kerick, Martin (Author) , Isau, Melanie (Author) , Timmermann, Bernd (Author) , Sültmann, Holger (Author) , Herwig, Ralf (Author) , Krobitsch, Sylvia (Author) , Schaefer, Georg (Author) , Verdorfer, Irmgard (Author) , Bartsch, Georg (Author) , Klocker, Helmut (Author) , Lehrach, Hans (Author) , Schweiger, Michal R. (Author)
Format: Article (Journal)
Language:English
Published: 29 September 2011
In: BMC medical genomics
Year: 2011, Volume: 4, Pages: 1-13
ISSN:1755-8794
DOI:10.1186/1755-8794-4-68
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1755-8794-4-68
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Author Notes:Martin Kerick, Melanie Isau, Bernd Timmermann, Holger Sültmann, Ralf Herwig, Sylvia Krobitsch, Georg Schaefer, Irmgard Verdorfer, Georg Bartsch, Helmut Klocker, Hans Lehrach and Michal R. Schweiger
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Summary:Massively parallel sequencing technologies have brought an enormous increase in sequencing throughput. However, these technologies need to be further improved with regard to reproducibility and applicability to clinical samples and settings.
Item Description:Gesehen am 28.07.2022
Physical Description:Online Resource
ISSN:1755-8794
DOI:10.1186/1755-8794-4-68