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A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer

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Christopher Haiman and colleagues report a genome-wide association study for estrogen receptor (ER)-negative breast cancer in women of African and European ancestry. They identify a variant at the TERT-CLPTM1L locus on 5p15 as associated with ER-negative and triple-negative breast cancer. This locus...

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Bibliographische Detailangaben
Hauptverfasser: Haiman, Christopher A. (VerfasserIn) , Canzian, Federico (VerfasserIn) , Chang-Claude, Jenny (VerfasserIn) , Hamann, Ute (VerfasserIn) , Kaaks, Rudolf (VerfasserIn) , Sinn, Peter (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 30 October 2011
In: Nature genetics
Year: 2011, Jahrgang: 43, Heft: 12, Pages: 1210-1214
ISSN:1546-1718
DOI:10.1038/ng.985
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/ng.985
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/ng.985
Volltext
Verfasserangaben:Christopher A. Haiman, Gary K. Chen, Celine M. Vachon, Federico Canzian, Alison Dunning, Robert C. Millikan, Xianshu Wang, Foluso Ademuyiwa, Shahana Ahmed, Christine B. Ambrosone, Laura Baglietto, Rosemary Balleine, Elisa V. Bandera, Matthias W. Beckmann, Christine D. Berg, Leslie Bernstein, Carl Blomqvist, William J. Blot, Hiltrud Brauch, Julie E. Buring, Lisa A. Carey, Jane E. Carpenter, Jenny Chang-Claude, Stephen J. Chanock, Daniel I. Chasman, Christine L. Clarke, Angela Cox, Simon S. Cross, Sandra L. Deming, Robert B. Diasio, Athanasios M. Dimopoulos, W. Ryan Driver, Thomas Dünnebier, Lorraine Durcan, Diana Eccles, Christopher K. Edlund, Arif B. Ekici, Peter A. Fasching, Heather S. Feigelson, Dieter Flesch-Janys, Florentia Fostira, Asta Försti, George Fountzilas, Susan M. Gerty, Graham G. Giles, Andrew K. Godwin, Paul Goodfellow, Nikki Graham, Dario Greco, Ute Hamann, Susan E. Hankinson, Arndt Hartmann, Rebecca Hein, Judith Heinz, Andrea Holbrook, Robert N. Hoover, Jennifer J. Hu, David J. Hunter, Sue A. Ingles, Astrid Irwanto, Jennifer Ivanovich, Esther M. John, Nicola Johnson, Arja Jukkola-Vuorinen, Rudolf Kaaks, Yon-Dschun Ko, Laurence N. Kolonel, Irene Konstantopoulou, Veli-Matti Kosma, Swati Kulkarni, Diether Lambrechts, Adam M. Lee, Loïc Le Marchand, Timothy Lesnick, Jianjun Liu, Sara Lindstrom, Arto Mannermaa, Sara Margolin, Nicholas G. Martin, Penelope Miron, Grant W. Montgomery, Heli Nevanlinna, Stephan Nickels, Sarah Nyante, Curtis Olswold, Julie Palmer, Harsh Pathak, Dimitrios Pectasides, Charles M. Perou, Julian Peto, Paul D. P. Pharoah, Loreall C. Pooler, Michael F. Press, Katri Pylkäs, Timothy R. Rebbeck, Jorge L. Rodriguez-Gil, Lynn Rosenberg, Eric Ross, Thomas Rüdiger, Isabel dos Santos Silva, Elinor Sawyer, Marjanka K. Schmidt, Rüdiger Schulz-Wendtland, Fredrick Schumacher, Gianluca Severi, Xin Sheng, Lisa B. Signorello, Hans-Peter Sinn, Kristen N. Stevens, Melissa C. Southey, William J. Tapper, Ian Tomlinson, Frans B. L. Hogervorst, Els Wauters, JoEllen Weaver, Hans Wildiers, Robert Winqvist, David Van Den Berg, Peggy Wan, Lucy Y. Xia, Drakoulis Yannoukakos, Wei Zheng, Regina G. Ziegler, Afshan Siddiq, Susan L. Slager, Daniel O. Stram, Douglas Easton, Peter Kraft, Brian E. Henderson & Fergus J. Couch
Beschreibung
Zusammenfassung:Christopher Haiman and colleagues report a genome-wide association study for estrogen receptor (ER)-negative breast cancer in women of African and European ancestry. They identify a variant at the TERT-CLPTM1L locus on 5p15 as associated with ER-negative and triple-negative breast cancer. This locus also harbors multiple variants associated with a range of other cancers.
Beschreibung:Gesehen am 29.07.2022
Beschreibung:Online Resource
ISSN:1546-1718
DOI:10.1038/ng.985

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