Artificial intelligence in liver diseases: improving diagnostics, prognostics and response prediction
Clinical routine in hepatology involves the diagnosis and treatment of a wide spectrum of metabolic, infectious, autoimmune and neoplastic diseases. Clinicians integrate qualitative and quantitative information from multiple data sources to make a diagnosis, prognosticate the disease course, and rec...
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| Main Authors: | , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2 February 2022
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| In: |
JHEP reports
Year: 2022, Volume: 4, Issue: 4, Pages: 1-11 |
| ISSN: | 2589-5559 |
| DOI: | 10.1016/j.jhepr.2022.100443 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.jhepr.2022.100443 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S2589555922000155 
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| Author Notes: | David Nam, Julius Chapiro, Valerie Paradis, Tobias Paul Seraphin, Jakob Nikolas Kather |
| Summary: | Clinical routine in hepatology involves the diagnosis and treatment of a wide spectrum of metabolic, infectious, autoimmune and neoplastic diseases. Clinicians integrate qualitative and quantitative information from multiple data sources to make a diagnosis, prognosticate the disease course, and recommend a treatment. In the last 5 years, advances in artificial intelligence (AI), particularly in deep learning, have made it possible to extract clinically relevant information from complex and diverse clinical datasets. In particular, histopathology and radiology image data contain diagnostic, prognostic and predictive information which AI can extract. Ultimately, such AI systems could be implemented in clinical routine as decision support tools. However, in the context of hepatology, this requires further large-scale clinical validation and regulatory approval. Herein, we summarise the state of the art in AI in hepatology with a particular focus on histopathology and radiology data. We present a roadmap for the further development of novel biomarkers in hepatology and outline critical obstacles which need to be overcome. |
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| Item Description: | Gesehen am 03.08.2022 |
| Physical Description: | Online Resource |
| ISSN: | 2589-5559 |
| DOI: | 10.1016/j.jhepr.2022.100443 |