cDC1 to cDC2: "Everything I do, Ido1 it for you"
Distinct dendritic cell (DC) subsets exert specific functions in immune regulation, but their communication with each other has remained elusive. In this issue of Immunity, Gargaro et al. identify the IDO1-Kyn-AHR axis as a metabolic signaling pathway through which conventional DC subsets communicat...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
14 June 2022
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| In: |
Immunity
Year: 2022, Volume: 55, Issue: 6, Pages: 967-970 |
| ISSN: | 1097-4180 |
| DOI: | 10.1016/j.immuni.2022.05.015 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.immuni.2022.05.015 |
| Author Notes: | Mirja Tamara Prentzell and Christiane A. Opitz |
| Summary: | Distinct dendritic cell (DC) subsets exert specific functions in immune regulation, but their communication with each other has remained elusive. In this issue of Immunity, Gargaro et al. identify the IDO1-Kyn-AHR axis as a metabolic signaling pathway through which conventional DC subsets communicate and induce tolerogenicity. |
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| Item Description: | Gesehen am 04.08.2022 |
| Physical Description: | Online Resource |
| ISSN: | 1097-4180 |
| DOI: | 10.1016/j.immuni.2022.05.015 |