cDC1 to cDC2: "Everything I do, Ido1 it for you"

Distinct dendritic cell (DC) subsets exert specific functions in immune regulation, but their communication with each other has remained elusive. In this issue of Immunity, Gargaro et al. identify the IDO1-Kyn-AHR axis as a metabolic signaling pathway through which conventional DC subsets communicat...

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Hauptverfasser: Prentzell, Mirja Tamara (VerfasserIn) , Opitz, Christiane (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 14 June 2022
In: Immunity
Year: 2022, Jahrgang: 55, Heft: 6, Pages: 967-970
ISSN:1097-4180
DOI:10.1016/j.immuni.2022.05.015
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.immuni.2022.05.015
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Verfasserangaben:Mirja Tamara Prentzell and Christiane A. Opitz
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Zusammenfassung:Distinct dendritic cell (DC) subsets exert specific functions in immune regulation, but their communication with each other has remained elusive. In this issue of Immunity, Gargaro et al. identify the IDO1-Kyn-AHR axis as a metabolic signaling pathway through which conventional DC subsets communicate and induce tolerogenicity.
Beschreibung:Gesehen am 04.08.2022
Beschreibung:Online Resource
ISSN:1097-4180
DOI:10.1016/j.immuni.2022.05.015