Common variants in breast cancer risk loci predispose to distinct tumor subtypes

Genome-wide association studies (GWAS) have identified multiple common breast cancer susceptibility variants. Many of these variants have differential associations by estrogen receptor (ER) status, but how these variants relate with other tumor features and intrinsic molecular subtypes is unclear.

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Main Authors: Ahearn, Thomas (Author) , Arndt, Volker (Author) , Becher, Heiko (Author) , Behrens, Sabine (Author) , Brenner, Hermann (Author) , Burwinkel, Barbara (Author) , Chang-Claude, Jenny (Author) , Jung, Audrey Y. (Author) , Kaaks, Rudolf (Author)
Format: Article (Journal)
Language:English
Published: 04 January 2022
In: Breast cancer research
Year: 2022, Volume: 24, Pages: 1-13
ISSN:1465-542X
DOI:10.1186/s13058-021-01484-x
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13058-021-01484-x
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Author Notes:Thomas U. Ahearn, Volker Arndt, Heiko Becher, Sabine Behrens, Hermann Brenner, Barbara Burwinkel, Jenny Chang-Claude, Audrey Jung, Rudolf Kaaks ... [und 196 weitere]
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Summary:Genome-wide association studies (GWAS) have identified multiple common breast cancer susceptibility variants. Many of these variants have differential associations by estrogen receptor (ER) status, but how these variants relate with other tumor features and intrinsic molecular subtypes is unclear.
Item Description:Gesehen am 19.08.2022
Physical Description:Online Resource
ISSN:1465-542X
DOI:10.1186/s13058-021-01484-x