MiR-1248: a new prognostic biomarker able to identify supratentorial hemispheric pediatric low-grade gliomas patients associated with progression

Pediatric low-grade gliomas (pLGGs), particularly incompletely resected supratentorial tumours, can undergo progression after surgery. However to date, there are no predictive biomarkers for progression. Here, we aimed to identify pLGG-specific microRNA signatures and evaluate their value as a progn...

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Main Authors: Catanzaro, Giuseppina (Author) , Besharat, Zein Mersini (Author) , Carai, Andrea (Author) , Jäger, Natalie (Author) , Splendiani, Elena (Author) , Colin, Carole (Author) , Po, Agnese (Author) , Chiacchiarini, Martina (Author) , Citarella, Anna (Author) , Gianno, Francesca (Author) , Cacchione, Antonella (Author) , Miele, Evelina (Author) , Diomedi Camassei, Francesca (Author) , Gessi, Marco (Author) , Massimi, Luca (Author) , Locatelli, Franco (Author) , Jones, David T. W. (Author) , Figarella-Branger, Dominique (Author) , Pfister, Stefan (Author) , Mastronuzzi, Angela (Author) , Giangaspero, Felice (Author) , Ferretti, Elisabetta (Author)
Format: Article (Journal)
Language:English
Published: 17 June 2022
In: Biomarker Research
Year: 2022, Volume: 10, Pages: 1-17
ISSN:2050-7771
DOI:10.1186/s40364-022-00389-x
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s40364-022-00389-x
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Author Notes:Giuseppina Catanzaro, Zein Mersini Besharat, Andrea Carai, Natalie Jäger, Elena Splendiani, Carole Colin, Agnese Po, Martina Chiacchiarini, Anna Citarella, Francesca Gianno, Antonella Cacchione, Evelina Miele, Francesca Diomedi Camassei, Marco Gessi, Luca Massimi, Franco Locatelli, David T. W. Jones, Dominique Figarella-Branger, Stefan M. Pfister, Angela Mastronuzzi, Felice Giangaspero and Elisabetta Ferretti
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Summary:Pediatric low-grade gliomas (pLGGs), particularly incompletely resected supratentorial tumours, can undergo progression after surgery. However to date, there are no predictive biomarkers for progression. Here, we aimed to identify pLGG-specific microRNA signatures and evaluate their value as a prognostic tool.
Item Description:Gesehen am 26.08.2022
Physical Description:Online Resource
ISSN:2050-7771
DOI:10.1186/s40364-022-00389-x