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Impact of lung function decline on time to hospitalisation events in systemic sclerosis-associated interstitial lung disease (SSc-ILD): a joint model analysis

Interstitial lung disease (ILD) is a common organ manifestation in systemic sclerosis (SSc) and is the leading cause of death in patients with SSc. A decline in forced vital capacity (FVC) is an indicator of ILD progression and is associated with mortality in patients with SSc-associated ILD (SSc-IL...

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Main Authors: Kreuter, Michael (Author) , Del Galdo, Francesco (Author) , Miede, Corinna (Author) , Khanna, Dinesh (Author) , Wuyts, Wim A. (Author) , Hummers, Laura K. (Author) , Alves, Margarida (Author) , Schoof, Nils (Author) , Stock, Christian (Author) , Allanore, Yannick (Author)
Format: Article (Journal)
Language:English
Published: JAN 10 2022
In: Arthritis Research & Therapy
Year: 2022, Volume: 24, Pages: 1-9
ISSN:1465-9913
DOI:10.1186/s13075-021-02710-9
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13075-021-02710-9
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Author Notes:Michael Kreuter, Francesco Del Galdo, Corinna Miede, Dinesh Khanna, Wim A. Wuyts, Laura K. Hummers, Margarida Alves, Nils Schoof, Christian Stock and Yannick Allanore
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Summary:Interstitial lung disease (ILD) is a common organ manifestation in systemic sclerosis (SSc) and is the leading cause of death in patients with SSc. A decline in forced vital capacity (FVC) is an indicator of ILD progression and is associated with mortality in patients with SSc-associated ILD (SSc-ILD). However, the relationship between FVC decline and hospitalisation events in patients with SSc-ILD is largely unknown. The objective of this post hoc analysis was to investigate the relationship between FVC decline and clinically important hospitalisation endpoints.
Item Description:Gesehen am 02.09.2022
Physical Description:Online Resource
ISSN:1465-9913
DOI:10.1186/s13075-021-02710-9

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