Impact of lung function decline on time to hospitalisation events in systemic sclerosis-associated interstitial lung disease (SSc-ILD): a joint model analysis

Interstitial lung disease (ILD) is a common organ manifestation in systemic sclerosis (SSc) and is the leading cause of death in patients with SSc. A decline in forced vital capacity (FVC) is an indicator of ILD progression and is associated with mortality in patients with SSc-associated ILD (SSc-IL...

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Hauptverfasser: Kreuter, Michael (VerfasserIn) , Del Galdo, Francesco (VerfasserIn) , Miede, Corinna (VerfasserIn) , Khanna, Dinesh (VerfasserIn) , Wuyts, Wim A. (VerfasserIn) , Hummers, Laura K. (VerfasserIn) , Alves, Margarida (VerfasserIn) , Schoof, Nils (VerfasserIn) , Stock, Christian (VerfasserIn) , Allanore, Yannick (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: JAN 10 2022
In: Arthritis Research & Therapy
Year: 2022, Jahrgang: 24, Pages: 1-9
ISSN:1465-9913
DOI:10.1186/s13075-021-02710-9
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13075-021-02710-9
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Verfasserangaben:Michael Kreuter, Francesco Del Galdo, Corinna Miede, Dinesh Khanna, Wim A. Wuyts, Laura K. Hummers, Margarida Alves, Nils Schoof, Christian Stock and Yannick Allanore

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520 |a Interstitial lung disease (ILD) is a common organ manifestation in systemic sclerosis (SSc) and is the leading cause of death in patients with SSc. A decline in forced vital capacity (FVC) is an indicator of ILD progression and is associated with mortality in patients with SSc-associated ILD (SSc-ILD). However, the relationship between FVC decline and hospitalisation events in patients with SSc-ILD is largely unknown. The objective of this post hoc analysis was to investigate the relationship between FVC decline and clinically important hospitalisation endpoints. 
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