Design of a multinational randomized controlled trial to assess the effects of structured and individualized exercise in patients with metastatic breast cancer on fatigue and quality of life: the EFFECT study

Many patients with metastatic breast cancer experience cancer- and treatment-related side effects that impair activities of daily living and negatively affect the quality of life. There is a need for interventions that improve quality of life by alleviating fatigue and other side effects during pall...

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Main Authors: Hiensch, Anouk E. (Author) , Monninkhof, Evelyn M. (Author) , Schmidt, Martina (Author) , Zopf, Eva M. (Author) , Bolam, Kate A. (Author) , Aaronson, Neil K. (Author) , Belloso, Jon (Author) , Bloch, Wilhelm (Author) , Clauss, Dorothea (Author) , Depenbusch, Johanna (Author) , Lachowicz, Milena (Author) , Pelaez, Mireia (Author) , Rundqvist, Helene (Author) , Senkus, Elzbieta (Author) , Stuiver, Martijn M. (Author) , Trevaskis, Mark (Author) , Urruticoechea, Ander (Author) , Rosenberger, Friederike (Author) , van der Wall, Elsken (Author) , de Wit, G. Ardine (Author) , Zimmer, Philipp (Author) , Wengström, Yvonne (Author) , Steindorf, Karen (Author) , May, Anne M. (Author)
Format: Article (Journal)
Language:English
Published: 29 July 2022
In: Trials
Year: 2022, Volume: 23, Pages: 1-14
ISSN:1468-6694
DOI:10.1186/s13063-022-06556-7
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13063-022-06556-7
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Author Notes:Anouk E. Hiensch, Evelyn M. Monninkhof, Martina E. Schmidt, Eva M. Zopf, Kate A. Bolam, Neil K. Aaronson, Jon Belloso, Wilhelm Bloch, Dorothea Clauss, Johanna Depenbusch, Milena Lachowicz, Mireia Pelaez, Helene Rundqvist, Elzbieta Senkus, Martijn M. Stuiver, Mark Trevaskis, Ander Urruticoechea, Friederike Rosenberger, Elsken van der Wall, G. Ardine de Wit, Philipp Zimmer, Yvonne Wengström, Karen Steindorf and Anne M. May
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Summary:Many patients with metastatic breast cancer experience cancer- and treatment-related side effects that impair activities of daily living and negatively affect the quality of life. There is a need for interventions that improve quality of life by alleviating fatigue and other side effects during palliative cancer treatment. Beneficial effects of exercise have been observed in the curative setting, but, to date, comparable evidence in patients with metastatic breast cancer is lacking. The aim of this study is to assess the effects of a structured and individualized 9-month exercise intervention in patients with metastatic breast cancer on quality of life, fatigue, and other cancer- and treatment-related side effects.
Item Description:Gesehen am 06.09.2022
Physical Description:Online Resource
ISSN:1468-6694
DOI:10.1186/s13063-022-06556-7