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Small renal cell carcinoma: oncological outcome with tumour size

OBJECTIVE: The aim of the study was to analyse oncological outcomes of patients with renal cell carcinoma (RCC) up to 4 cm in diameter. - MATERIAL AND METHODS: A consecutive series of 396 patients with small RCC was analysed. Tumours were stratified by diameter into three groups: 2 cm (n = 68) for t...

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Hauptverfasser: Pahernik, Sascha (VerfasserIn) , Huber, Johannes (VerfasserIn) , Pfitzenmaier, Jesco (VerfasserIn) , Haferkamp, Axel (VerfasserIn) , Hohenfellner, Markus (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 24 October 2011
In: Scandinavian journal of urology and nephrology
Year: 2011, Jahrgang: 45, Heft: 6, Pages: 432-435
ISSN:1651-2065
DOI:10.3109/00365599.2011.621143
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3109/00365599.2011.621143
Volltext
Verfasserangaben:Sascha Pahernik, Johannes Huber, Jesco Pfitzenmaier, Axel Haferkamp & Markus Hohenfellner
Beschreibung
Zusammenfassung:OBJECTIVE: The aim of the study was to analyse oncological outcomes of patients with renal cell carcinoma (RCC) up to 4 cm in diameter. - MATERIAL AND METHODS: A consecutive series of 396 patients with small RCC was analysed. Tumours were stratified by diameter into three groups: 2 cm (n = 68) for tumours up to 2 cm, 3 cm (n = 172) for tumours between 2.1 and 3.0 cm, and 4 cm (n = 156) for tumours between 3.1 and 4.0 cm in diameter. - RESULTS: Tumour stages were distributed into pT1a in 95.6%, 91.9% and 87.0% and into pT3 in 4.4%, 8.1% and 13.0% for the 2 cm, 3 cm and 4 cm groups, respectively. Metastases at the time of diagnosis were found in 2.9% (n = 2), 7.5% (n = 13) and 9.1% (n = 14) of patients in the 2 cm, 3 cm and 4 cm groups, respectively. The tumour-specific survival was 100%, 96.9% and 94.6% at 1 year, 97.5%, 90.3% and 87.5% at 5 years and 97.5%, 87.3% and 84.1% at 10 years for the 2 cm, 3 cm and 4 cm groups, respectively (p < 0.05). - CONCLUSIONS: Negative prognostic features as well as worse oncological outcome increase with tumour diameter above 2 cm. These data have important implications when considering active surveillance of small renal tumours.
Beschreibung:Gesehen am 06.09.2022
Beschreibung:Online Resource
ISSN:1651-2065
DOI:10.3109/00365599.2011.621143

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