Successful thrombolysis and spasmolysis of acute leg ischemia after accidental intra-arterial injection of dissolved flunitrazepam tablets

A 37-year-old man with known intravenous drug abuse presented in the surgical ambulatory care unit with acute leg ischemia after accidental intra-arterial injection of dissolved flunitrazepam tablets into the right femoral artery. A combination of anticoagulation, vasodilatation, and local selective...

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Main Authors: Radeleff, Boris (Author) , Stampfl, Ulrike (Author) , Sommer, Christof-Matthias (Author) , Bellemann, Nadine (Author) , Hyhlik-Dürr, Alexander (Author) , Weber, Marc-André (Author) , Böckler, Dittmar (Author) , Kauczor, Hans-Ulrich (Author)
Format: Article (Journal)
Language:English
Published: 07 May 2011
In: CardioVascular and interventional radiology
Year: 2011, Volume: 34, Issue: 5, Pages: 1085-1089
ISSN:1432-086X
DOI:10.1007/s00270-011-0173-3
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00270-011-0173-3
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Author Notes:B. Radeleff, U. Stampfl, C.-M. Sommer, N. Bellemann, A. Hyhlik-Duerr, M.-A. Weber, D. Boeckler, H.-U. Kauczor
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Summary:A 37-year-old man with known intravenous drug abuse presented in the surgical ambulatory care unit with acute leg ischemia after accidental intra-arterial injection of dissolved flunitrazepam tablets into the right femoral artery. A combination of anticoagulation, vasodilatation, and local selective and superselective thrombolysis with urokinase was performed to salvage the leg. As a result of the severe ischemia-induced pain, the patient had to be monitored over the complete therapy period on the intensive care unit with permanent administration of intravenous fluid and analgetics. We describe the presenting symptoms and the interventional technique, and we discuss the recent literature regarding the management of accidental intra-arterial injection of dissolved flunitrazepam tablets.
Item Description:Gesehen am 08.09.2022
Physical Description:Online Resource
ISSN:1432-086X
DOI:10.1007/s00270-011-0173-3