Systematic review and meta-analysis on the associations of polypharmacy and potentially inappropriate medication with adverse outcomes in older cancer patients

Both polypharmacy and potentially inappropriate medication (PIM) intake are highly prevailing in older cancer patients. However, only studies on the association of polypharmacy and postoperative complications have been meta-analyzed previously. A systematic review and a meta-analysis of prospective/...

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Main Authors: Chen, Li-Ju (Author) , Trares, Kira (Author) , Laetsch, Dana Clarissa (Author) , Nguyen, Thi Ngoc Mai (Author) , Brenner, Hermann (Author) , Schöttker, Ben (Author)
Format: Article (Journal)
Language:English
Published: May 27, 2020
In: The journals of gerontology. Series A, Biological sciences, medical sciences
Year: 2021, Volume: 76, Issue: 6, Pages: 1044-1052
ISSN:1758-535X
DOI:10.1093/gerona/glaa128
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1093/gerona/glaa128
Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/biomedgerontology/article/76/6/1044/5847835?login=true
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Author Notes:Li-Ju Chen, Kira Trares, Dana Clarissa Laetsch, Thi Ngoc Mai Nguyen, Hermann Brenner, and Ben Schöttker
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Summary:Both polypharmacy and potentially inappropriate medication (PIM) intake are highly prevailing in older cancer patients. However, only studies on the association of polypharmacy and postoperative complications have been meta-analyzed previously. A systematic review and a meta-analysis of prospective/retrospective observational studies reporting associations of polypharmacy or PIM with at least one out of five predefined adverse health outcomes in a population of older cancer patients (≥60 years) were carried out.
Item Description:Gesehen am 14.09.2022
Physical Description:Online Resource
ISSN:1758-535X
DOI:10.1093/gerona/glaa128