Advanced vibrational spectroscopy for biomedical applications: University of Cambridge, United Kingdom, 21-23 March 2016

Infrared micro-spectroscopy of human tissue: principles and future promises /Max Diem [and 5 others] --Development of a practical spatial-spectral analysis protocol for breast histopathology using Fourier transform spectroscopic imaging /F. Nell Pounder, Rohith K. Reddy and Rohit Bhargava --FTIR spe...

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Other Authors: Gardner, Peter (Editor)
Format: Conference Paper
Language:English
Published: Cambridge Royal Society of Chemistry 2016
Series:Faraday discussions volume 187
In: Faraday discussions (volume 187)

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Online Access:Verlag: http://pubs.rsc.org/en/journals/journalissues/fd#!issueid=fd016187
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Author Notes:chair Peter Gardner (University of Manchester, UK) ; Faraday Division of the Royal Society of Chemistry
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Summary:Infrared micro-spectroscopy of human tissue: principles and future promises /Max Diem [and 5 others] --Development of a practical spatial-spectral analysis protocol for breast histopathology using Fourier transform spectroscopic imaging /F. Nell Pounder, Rohith K. Reddy and Rohit Bhargava --FTIR spectroscopic imaging and mapping with correcting lenses for studies of biological cells and tissues /James A. Kimber, Liberty Foreman, Benjamin Turner, Peter Rich and Sergei G. Kazarian --Multi-centre Raman spectral mapping of oesophagael cancer tissues: a study to assess system transferability /M. Isabelle [and 13 others] --Label-free classification of colon cancer grading using infrared spectral histopathology /C. Kuepper [and 5 others] --Advancements in quantum cascade laser-based infrared microscopy of aqueous media /K. Haase, N. Kröger-Lui, A. Pucci, A. Schönhals and W. Petrich --High-throughput quantum cascade laser (QCL) spectral histopathology: a practical approach towards clinical translation /Michael J. Pilling [and 5 others] --Spectral pathology: general discussion --Raman spectroscopy for cytopathology of exfoliated cervical cells /I. R. Ramos [and 7 others] --Towards quantitative molecular mapping of cells by Raman microscopy: using AFM for decoupling molecular concentration and cell topography /Radu Boitor, Faris Sinjab, Stephanie Strohbuecker, Virginie Sottile and Ioan Notingher --Vibrational spectroscopy in sensing radiobiological effects: analyses of targeted and non-targeted effects in human keratinocytes /Aidan D. Meade [and 5 others] --Mie scatter corrections in single cell infrared microspectroscopy /Tatiana Konevskikh, Rozalia Lukacs, Reinhold Blümel, Arkadi Ponossov and Achim Kohler --Infrared imaging of small molecules in living cells: from in vitro metabolic analysis to cytopathology /Luca Quaroni, Theodora Zlateva, Katia Wehbe and Gianfelice Cinque --Chemotherapeutic response to cisplatin-like drugs in human breast cancer cells probed by vibrational microspectroscopy /A. L. M. Batista de Carvalho [and 8 others] --Single cell analysis/data handling: general discussion --Non-invasive chemically specific measurement of subsurface temperature in biological tissues using surface-enhanced spatially offset Raman spectroscopy /Benjamin Gardner, Nicholas Stone and Pavel Matousek --High resolution FTIR imaging provides automated discrimination and detection of single malaria parasite infected erythrocytes on glass /David Perez-Guaita [and 6 others] --Rapid characterization of Klebsiella oxytoca isolates from contaminated liquid hand soap using mass spectrometry, FTIR and Raman spectroscopy /Ralf Dieckmann [and 9 others] --Fiber-optic Raman spectroscopy for in vivo diagnosis of gastric dysplasia /Jianfeng Wang [and 6 others] --Investigation of intervertebral disc degeneration using multivariate FTIR spectroscopic imaging /Kerstin T. Mader [and 6 others] --Assessing corneal biomechanics with Brillouin spectro-microscopy /Guillaume Lepert, Ricardo M. Gouveia, Che J. Connon and Carl Paterson --Clinical spectroscopy: general discussion --From synthetic DNA to PCR product: detection of fungal infections using SERS /Samuel Mabbott [and 5 others] --Sheath flow SERS for chemical profiling in urine /Colleen M. Riordan, Kevin T. Jacobs, Pierre Negri and Zachary D. Schultz --Towards SERS-based point-of-care approaches for therapeutic drug monitoring: the case of methotrexate /Stefano Fornasaro, Silvia Dalla Marta, Marco Rabusin, Alois Bonifacio and Valter Sergo --SERS as a tool for in vitro toxicology /Kate M. Fisher [and 7 others] --Biofluid infrared spectro-diagnostics: pre-analytical considerations for clinical applications /L. Lovergne [and 6 others] --New IR imaging modalities for cancer detection and for intra-cell chemical mapping with a sub-diffraction mid-IR s-SNOM /H. Amrania [and 8 others] --High spatial resolution (1.1 [mu]m and 20 nm) FTIR polarization contrast imaging reveals pre-rupture disorder in damaged tendon /Richard Wiens [and 6 others] -- Biofluids and other techniques: general discussion --Translating vibrational spectroscopy into clinical applications: vision or reality? /Wolfgang Petrich.
This volume focuses on the cutting edge of vibrational spectroscopy and development of clinically relevant diagnostic tools for current challenges and emerging opportunities in biomedical applications. There have been significant advances in vibrational biomedical spectroscopy and many aspects of associated biophotonics in recent years. Large array detectors suitable for rapid scanning FTIR are now commonplace, tuneable infrared quantum cascade lasers are now available, deep Raman spectroscopy has emerged as a significant breakthrough technique and nonlinear Raman microscopes offer exciting new possibilities in the area of cell biology. There has also been a revolution in near field methods (e.g. tip enhanced Raman and Infrared, TERS AFM-IR, SNOM), all of which have been used on biomedical samples and accelerator based infrared sources continue to evolve. Diagnostic and prognostic tools based on these new technologies have the potential to revolutionise our clinical systems leading to improved patient outcome, more efficient public services and significant economic savings for healthcare providers and society. There are, however, many fundamental scientific and technological questions that we need to address before such techniques can be incorporated into the clinical arena
Item Description:"A general discussion on Advanced Vibrational Spectroscopy for Biomedical Applications was held in Cambridge, UK on the 21st, 22nd and 23rd of March 2016"--Page 5
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