Revitalization of cortical bone allograft by application of vascularized scaffolds seeded with osteogenic induced adipose tissue derived stem cells in a rabbit model

Adipogenous tissue derived stem cells (ASC) are available in abundance in the human body and can differentiate in the presence of lineage-specific induction factors, for example, in myogenic, adipogenic, chondrogenic and osteogenic cells. The aim of this study was to evaluate the impact of osteogeni...

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Main Authors: Kloeters, Oliver (Author) , Berger, Irina (Author) , Ryssel, Henning (Author) , Megerle, Kai Oliver (Author) , Leimer, Uwe (Author) , Germann, Günter (Author)
Format: Article (Journal)
Language:English
Published: 19 May 2011
In: Archives of orthopaedic and trauma surgery
Year: 2011, Volume: 131, Issue: 10, Pages: 1459-1466
ISSN:1434-3916
DOI:10.1007/s00402-011-1306-5
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00402-011-1306-5
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Author Notes:Oliver Kloeters, Irina Berger, Henning Ryssel, Kai Megerle, Uwe Leimer, Günter Germann
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Summary:Adipogenous tissue derived stem cells (ASC) are available in abundance in the human body and can differentiate in the presence of lineage-specific induction factors, for example, in myogenic, adipogenic, chondrogenic and osteogenic cells. The aim of this study was to evaluate the impact of osteogenic induced ASC’s (O-ASC) on revascularization and cellular repopulation of avital cortical bone employing a vascularized bovine scaffold.
Item Description:Gesehen am 19.09.2022
Physical Description:Online Resource
ISSN:1434-3916
DOI:10.1007/s00402-011-1306-5