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Low-frequency sampling for PRx calculation does not reduce prognostication and produces similar CPPopt in intracerebral haemorrhage patients

The cerebral pressure reactivity index (PRx) correlates with the outcome in intracerebral haemorrhage (ICH) patients and has been used to define an autoregulation-oriented “optimal cerebral perfusion pressure” (CPPopt). PRx has been calculated as a moving correlation coefficient between mean arteria...

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Main Authors: Santos, Edgar (Author) , Diedler, Jennifer (Author) , Sykora, Marek (Author) , Orakcioglu, Berk (Author) , Kentar, Modar (Author) , Czosnyka, Marek (Author) , Unterberg, Andreas (Author) , Sakowitz, Oliver (Author)
Format: Article (Journal)
Language:English
Published: 11 September 2011
In: Acta neurochirurgica
Year: 2011, Volume: 153, Issue: 11, Pages: 2189-2195
ISSN:0942-0940
DOI:10.1007/s00701-011-1148-5
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00701-011-1148-5
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Author Notes:Edgar Santos, Jennifer Diedler, Marek Sykora, Berk Orakcioglu, Modar Kentar, Marek Czosnyka, Andreas Unterberg, Oliver W. Sakowitz
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Summary:The cerebral pressure reactivity index (PRx) correlates with the outcome in intracerebral haemorrhage (ICH) patients and has been used to define an autoregulation-oriented “optimal cerebral perfusion pressure” (CPPopt). PRx has been calculated as a moving correlation coefficient between mean arterial pressure (MAP) and intracranial pressure (ICP) averaged over 5-10 s, using a 2.5- to 5-min moving time window, in order to reflect changes in MAP and ICP within a time frame of 20 s to 2 min. We compared PRx with a different calculation method [low-frequency PRx (L-PRx)], where rapid fluctuations of MAP and ICP are cancelled (waves with frequencies greater than 0.01 Hz).
Item Description:Gesehen am 06.10.2022
Physical Description:Online Resource
ISSN:0942-0940
DOI:10.1007/s00701-011-1148-5

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