Telomerase subunit Est2 marks internal sites that are prone to accumulate DNA damage

The main function of telomerase is at the telomeres but under adverse conditions telomerase can bind to internal regions causing deleterious effects as observed in cancer cells.

Saved in:

Bibliographic Details
Main Authors:	Pandey, Satyaprakash (Author) , Hajikazemi, Mona (Author) , Zacheja, Theresa (Author) , Schalbetter, Stephanie (Author) , Neale, Matthew J. (Author) , Baxter, Jonathan (Author) , Guryev, Victor (Author) , Hofmann, Andreas (Author) , Heermann, Dieter W. (Author) , Juranek, Stefan A. (Author) , Paeschke, Katrin (Author)
Format:	Article (Journal)
Language:	English
Published:	20 November 2021
In:	BMC biology Year: 2021, Volume: 19, Pages: 1-15
ISSN:	1741-7007
DOI:	10.1186/s12915-021-01167-1
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12915-021-01167-1
Author Notes:	Satyaprakash Pandey, Mona Hajikazemi, Theresa Zacheja, Stephanie Schalbetter, Matthew J. Neale, Jonathan Baxter, Victor Guryev, Andreas Hofmann, Dieter W. Heermann, Stefan A. Juranek and Katrin Paeschke

Description
Summary:	The main function of telomerase is at the telomeres but under adverse conditions telomerase can bind to internal regions causing deleterious effects as observed in cancer cells.
Item Description:	Gesehen am 11.10.2022
Physical Description:	Online Resource
ISSN:	1741-7007
DOI:	10.1186/s12915-021-01167-1