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Evaluation of process parameter of an automated dip-coating

Dip coating is a common technique for the optimization of metallic implants, whereas several steps during the procedure influence the coating. This study aims in the development of a coating apparatus and the evaluation of critical steps, such as mixing, immersion, retention and withdrawal velocity...

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Bibliographische Detailangaben
Hauptverfasser: Strobel, Catrin (VerfasserIn) , Kadow-Romacker, Anke (VerfasserIn) , Witascheck, Tom (VerfasserIn) , Schmidmaier, Gerhard (VerfasserIn) , Wildemann, Britt (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 5 August 2011
In: Materials letters
Year: 2011, Jahrgang: 65, Heft: 23, Pages: 3621-3624
ISSN:1873-4979
DOI:10.1016/j.matlet.2011.07.102
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.matlet.2011.07.102
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0167577X11008822
Volltext
Verfasserangaben:Catrin Strobel, Anke Kadow-Romacker, Tom Witascheck, Gerhard Schmidmaier, Britt Wildemann
Beschreibung
Zusammenfassung:Dip coating is a common technique for the optimization of metallic implants, whereas several steps during the procedure influence the coating. This study aims in the development of a coating apparatus and the evaluation of critical steps, such as mixing, immersion, retention and withdrawal velocity during the procedure. In addition the influence of the polymer solution viscosity, poly(d,l-lactide) dissolved in ethyl acetate, was analyzed. As a therapeutic drug, gentamicin was incorporated and the amount in the different coatings quantified. With increased withdrawal velocity and viscosity the thickness of the coating layer increased. This was accompanied by an increase in incorporated drug. The mixing, immersion and retention time had almost no effect. The viscosity of the polymer solution and the withdrawal velocity can therefore be used to modify bioactive coatings for optimized local drug loading.
Beschreibung:Gesehen am 24.10.2022
Beschreibung:Online Resource
ISSN:1873-4979
DOI:10.1016/j.matlet.2011.07.102

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