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AMAZONE: prevention of persistent pain after breast cancer treatment by online cognitive behavioral therapy$dstudy protocol of a randomized controlled multicenter trial

Surviving breast cancer does not necessarily mean complete recovery to a premorbid state of health. Among the multiple psychological and somatic symptoms that reduce the quality of life of breast cancer survivors, persistent pain after breast cancer treatment (PPBCT) with a prevalence of 15-65% is p...

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Main Authors: Lukas, Anne (Author) , Theunissen, Maurice (Author) , Boer, Dianne de Korte-de (Author) , Kuijk, Sander van (Author) , Noyen, Lotte van (Author) , Magerl, Walter (Author) , Mess, Werner H. (Author) , Buhre, Wolfgang Friedrich (Author) , Peters, Madelon (Author)
Format: Article (Journal)
Language:English
Published: 25 July 2022
In: Trials
Year: 2022, Volume: 23, Pages: 1-14
ISSN:1468-6694
DOI:10.1186/s13063-022-06549-6
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13063-022-06549-6
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Author Notes:Anne Lukas, Maurice Theunissen, Dianne de Korte-de Boer, Sander van Kuijk, Lotte Van Noyen, Walter Magerl, Werner Mess, Wolfgang Buhre and Madelon Peters
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Summary:Surviving breast cancer does not necessarily mean complete recovery to a premorbid state of health. Among the multiple psychological and somatic symptoms that reduce the quality of life of breast cancer survivors, persistent pain after breast cancer treatment (PPBCT) with a prevalence of 15-65% is probably the most invalidating. Once chronic, PPBCT is difficult to treat and requires an individualized multidisciplinary approach. In the past decades, several somatic and psychological risk factors for PPBCT have been identified. Studies aiming to prevent PPBCT by reducing perioperative pain intensity have not yet shown a significant reduction of PPBCT prevalence. Only few studies have been performed to modify psychological distress around breast cancer surgery. The AMAZONE study aims to investigate the effect of online cognitive behavioral therapy (e-CBT) on the prevalence of PPBCT.
Item Description:Gesehen am 08.11.2022
Physical Description:Online Resource
ISSN:1468-6694
DOI:10.1186/s13063-022-06549-6

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