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Identification of NHLRC1 as a novel AKT activator from a lung cancer epigenome-wide association study (EWAS)

Changes in DNA methylation identified by epigenome-wide association studies (EWAS) have been recently linked to increased lung cancer risk. However, the cellular effects of these differentially methylated positions (DMPs) are often unclear. Therefore, we investigated top differentially methylated po...

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Main Authors: Faltus, Christian (Author) , Lahnsteiner, Angelika (Author) , Barrdahl, Myrto (Author) , Assenov, Yassen (Author) , Hüsing, Anika (Author) , Bogatyrova, Olga (Author) , Laplana, Marina (Author) , Johnson, Theron S. (Author) , Muley, Thomas (Author) , Meister, Michael (Author) , Warth, Arne (Author) , Thomas, Michael (Author) , Plass, Christoph (Author) , Kaaks, Rudolf (Author) , Risch, Angela (Author)
Format: Article (Journal)
Language:English
Published: 14 September 2022
In: International journal of molecular sciences
Year: 2022, Volume: 23, Issue: 18, Pages: 1-18
ISSN:1422-0067
DOI:10.3390/ijms231810699
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.3390/ijms231810699
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/1422-0067/23/18/10699
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Author Notes:Christian Faltus, Angelika Lahnsteiner, Myrto Barrdahl, Yassen Assenov, Anika Hüsing, Olga Bogatyrova, Marina Laplana, Theron Johnson, Thomas Muley, Michael Meister, Arne Warth, Michael Thomas, Christoph Plass, Rudolf Kaaks and Angela Risch
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Summary:Changes in DNA methylation identified by epigenome-wide association studies (EWAS) have been recently linked to increased lung cancer risk. However, the cellular effects of these differentially methylated positions (DMPs) are often unclear. Therefore, we investigated top differentially methylated positions identified from an EWAS study.
Item Description:Gesehen am 15.11.2022
Physical Description:Online Resource
ISSN:1422-0067
DOI:10.3390/ijms231810699

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