Detection of isocitrate dehydrogenase 1 mutation R132H in myelodysplastic syndrome by mutation-specific antibody and direct sequencing

Sequencing of the acute myeloid leukemia genome revealed somatic mutations in isocitrate dehydrogenase-1. Acute myeloid leukemia frequently develops from myelodysplastic syndrome. In order to test whether myelodysplastic syndrome also carries isocitrate dehydrogenase-1 mutations, we stained a series...

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Main Authors: Andrulis, Mindaugas (Author) , Capper, David (Author) , Luft, Thomas (Author) , Hartmann, Christian (Author) , Zentgraf, Hanswalter (Author) , Deimling, Andreas von (Author)
Format: Article (Journal)
Language:English
Published: 12 March 2010
In: Leukemia research
Year: 2010, Volume: 34, Issue: 8, Pages: 1091-1093
ISSN:1873-5835
DOI:10.1016/j.leukres.2010.02.014
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.leukres.2010.02.014
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0145212610000950
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Author Notes:Mindaugas Andrulis, David Capper, Thomas Luft, Christian Hartmann, Hanswalter Zentgraf, Andreas von Deimling
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