Mismatch repair deficiency, chemotherapy and survival for resectable gastric cancer: an observational study from the German staR cohort and a meta-analysis$doriginal article : clinical oncology
In a post hoc analysis of the MAGIC trial, patients with curatively resected gastric cancer (GC) and mismatch repair (MMR) deficiency (MMRd) had better median overall survival (OS) when treated with surgery alone but worse median OS when treated with additional chemotherapy. Further data are require...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
March 2023
|
| In: |
Journal of cancer research and clinical oncology
Year: 2023, Jahrgang: 149, Heft: 3, Pages: 1007-1017 |
| ISSN: | 1432-1335 |
| DOI: | 10.1007/s00432-022-03953-y |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00432-022-03953-y Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00432-022-03953-y |
| Verfasserangaben: | T. Stolze, S. Franke, J. Haybaeck, M. Moehler, P.P. Grimminger, H. Lang, W. Roth, I. Gockel, N. Kreuser, H. Bläker, C. Wittekind, F. Lordick, M. Vieth, L. Veits, O. Waidmann, P. Lingohr, U. Peitz, C. Schildberg, M. Kruschewski, N. Vassos, E. Goni, C.J. Bruns, K. Ridwelski, S. Wolff, H. Lippert, J. Schumacher, P. Malfertheiner, M. Venerito |
| Zusammenfassung: | In a post hoc analysis of the MAGIC trial, patients with curatively resected gastric cancer (GC) and mismatch repair (MMR) deficiency (MMRd) had better median overall survival (OS) when treated with surgery alone but worse median OS when treated with additional chemotherapy. Further data are required to corroborate these findings. |
|---|---|
| Beschreibung: | Online veröffentlicht: 25. Februar 2022 Gesehen am 29.07.2024 |
| Beschreibung: | Online Resource |
| ISSN: | 1432-1335 |
| DOI: | 10.1007/s00432-022-03953-y |