A novel and efficient one-pot synthesis of 2-aminopyrimidinones and their self-assembly = two
A three-component reaction of benzaldehyde derivatives, methyl cyanoacetate, and guanidinium carbonate affords 2-amino-4-aryl-1,6-dihydro-6-oxopyrimidine-5-carbonitriles and the four-component reaction of benzaldehyde derivatives, methyl cyanoacetate, and guanidinium hydrochloride in the presence of...
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
15 April 2010
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| In: |
Helvetica chimica acta
Year: 2010, Volume: 93, Issue: 4, Pages: 777-784 |
| ISSN: | 1522-2675 |
| DOI: | 10.1002/hlca.200900319 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/hlca.200900319 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/hlca.200900319 
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| Author Notes: | Morteza Bararjanian, Saeed Balalaie, Frank Rominger, and Sanaz Barouti |
| Summary: | A three-component reaction of benzaldehyde derivatives, methyl cyanoacetate, and guanidinium carbonate affords 2-amino-4-aryl-1,6-dihydro-6-oxopyrimidine-5-carbonitriles and the four-component reaction of benzaldehyde derivatives, methyl cyanoacetate, and guanidinium hydrochloride in the presence of piperidine leads to piperidinium salts of pyrimidinones. X-ray crystallography data confirm self-assembly and H-bonding in these compounds. |
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| Item Description: | Gesehen am 01.12.2022 |
| Physical Description: | Online Resource |
| ISSN: | 1522-2675 |
| DOI: | 10.1002/hlca.200900319 |