Artificial intelligence in histopathology: enhancing cancer research and clinical oncology

Artificial intelligence (AI) methods have multiplied our capabilities to extract quantitative information from digital histopathology images. AI is expected to reduce workload for human experts, improve the objectivity and consistency of pathology reports, and have a clinical impact by extracting hi...

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Hauptverfasser: Shmatko, Artem (VerfasserIn) , Ghaffari Laleh, Narmin (VerfasserIn) , Gerstung, Moritz (VerfasserIn) , Kather, Jakob Nikolas (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 22 September 2022
In: Nature cancer
Year: 2022, Jahrgang: 3, Heft: 9, Pages: 1026-1038
ISSN:2662-1347
DOI:10.1038/s43018-022-00436-4
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s43018-022-00436-4
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s43018-022-00436-4
Volltext
Verfasserangaben:Artem Shmatko, Narmin Ghaffari Laleh, Moritz Gerstung and Jakob Nikolas Kather
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Zusammenfassung:Artificial intelligence (AI) methods have multiplied our capabilities to extract quantitative information from digital histopathology images. AI is expected to reduce workload for human experts, improve the objectivity and consistency of pathology reports, and have a clinical impact by extracting hidden information from routinely available data. Here, we describe how AI can be used to predict cancer outcome, treatment response, genetic alterations and gene expression from digitized histopathology slides. We summarize the underlying technologies and emerging approaches, noting limitations, including the need for data sharing and standards. Finally, we discuss the broader implications of AI in cancer research and oncology.
Beschreibung:Gesehen am 05.12.2022
Beschreibung:Online Resource
ISSN:2662-1347
DOI:10.1038/s43018-022-00436-4