The impact of tumor metabolic activity assessed by 18F-FET amino acid PET imaging in particle radiotherapy of high-grade glioma patients

Selective uptake of (18)F-fluoro-ethyl-tyrosine (18F-FET) is used in high-grade glioma (HGG) to assess tumor metabolic activity via positron emission tomography (PET). We aim to investigate its value for target volume definition, as a prognosticator, and associations with whole-blood transcriptome l...

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Main Authors:	Waltenberger, Maria (Author) , Furkel, Jennifer (Author) , Röhrich, Manuel (Author) , Salome, Patrick (Author) , Debus, Charlotte (Author) , Tawk, Bouchra (Author) , Gahlawat, Aoife Ward (Author) , Kudak, Andreas (Author) , Dostal, Matthias (Author) , Wirkner, Ute (Author) , Schwager, Christian (Author) , Herold-Mende, Christel (Author) , Combs, Stephanie (Author) , König, Laila (Author) , Debus, Jürgen (Author) , Haberkorn, Uwe (Author) , Abdollahi, Amir (Author) , Knoll, Maximilian (Author)
Format:	Article (Journal)
Language:	English
Published:	20 September 2022
In:	Frontiers in oncology Year: 2022, Volume: 12, Pages: 1-15
ISSN:	2234-943X
DOI:	10.3389/fonc.2022.901390
Online Access:	Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.3389/fonc.2022.901390 Verlag, lizenzpflichtig, Volltext: https://www.frontiersin.org/articles/10.3389/fonc.2022.901390
Author Notes:	Maria Waltenberger, Jennifer Furkel, Manuel Röhrich, Patrick Salome, Charlotte Debus, Bouchra Tawk, Aoife Ward Gahlawat, Andreas Kudak, Matthias Dostal, Ute Wirkner, Christian Schwager, Christel Herold-Mende, Stephanie E. Combs, Laila König, Jürgen Debus, Uwe Haberkorn, Amir Abdollahi and Maximilian Knoll