Microsurgical strategies after free flap failure in soft tissue reconstruction of the lower extremity: a 17-year single-center experience

Background: There is no clear consensus on the optimal surgical strategy for providing safe coverage in salvage free flap surgery after total free flap failure. Methods: A retrospective study was conducted to evaluate patients with total failure of the primary free flap in lower extremity reconstruc...

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Main Authors: Strübing, Felix (Author) , Xiong, Lingyun (Author) , Bigdeli, Amir K. (Author) , Diehm, Yannick (Author) , Kneser, Ulrich (Author) , Hirche, Christoph (Author) , Gazyakan, Emre (Author)
Format: Article (Journal)
Language:English
Published: 22 September 2022
In: Journal of Personalized Medicine
Year: 2022, Volume: 12, Issue: 10, Pages: 1-16
ISSN:2075-4426
DOI:10.3390/jpm12101563
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/jpm12101563
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/2075-4426/12/10/1563
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Author Notes:Felix Struebing, Lingyun Xiong, Amir K. Bigdeli, Yannick Diehm, Ulrich Kneser, Christoph Hirche and Emre Gazyakan
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Summary:Background: There is no clear consensus on the optimal surgical strategy for providing safe coverage in salvage free flap surgery after total free flap failure. Methods: A retrospective study was conducted to evaluate patients with total failure of the primary free flap in lower extremity reconstruction between 2000 and 2017. Results: In a cohort of 1.016 patients, we identified 43 cases of total flap failure (4.2%). A total of 30 patients received a salvage free flap with a success rate of 83.3% (25/30). One patient received a secondary salvage free flap. Overall limb salvage after primary free flap loss was 83.7% (36/43). Conclusions: Microsurgical management of free flap loss in the lower extremity is challenging and requires a decisive re-evaluation of risk factors and alternative strategies. This should include reconsidering the flap choice with a tendency towards traditional and safe workhorse flaps, a low-threshold switch to different recipient vessels, including arteriovenous (AV) loops, bypasses (especially in case of venous insufficiency) and back-up procedures, such as negative pressure wound therapy or dermal regeneration templates with skin grafting in cases of lower demand and critically ill patients. We derived one suggestion from our previous practice: replacing perforator flaps with axial pattern flaps (“safe workhorses”).
Item Description:Gesehen am 09.12.2022
Physical Description:Online Resource
ISSN:2075-4426
DOI:10.3390/jpm12101563