Regio- and diastereoselective transition metal-free hydroalkylation of N-allenyl sulfonamides by push-pull 2-alkynylquinolines
We describe a novel and efficient synthetic strategy to construct the linear homoallylic quinolone structures through the intermolecular addition of 2-alkynylquinoline to N-allenyl sulfonamides. We developed the regio- and diastereoselective transition metal-free hydroalkylation of 1,2-dienes by a s...
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| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
07 Oct 2022
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| In: |
Organic & biomolecular chemistry
Year: 2022, Jahrgang: 20, Heft: 42, Pages: 8269-8272 |
| ISSN: | 1477-0539 |
| DOI: | 10.1039/D2OB01362B |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1039/D2OB01362B Verlag, lizenzpflichtig, Volltext: https://pubs.rsc.org/en/content/articlelanding/2022/ob/d2ob01362b 
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| Verfasserangaben: | Reza Dehghanpour Kalan, Kamran Amiri, Frank Rominger, Saeed Balalaie and Hamid Reza Bijanzadeh |
| Zusammenfassung: | We describe a novel and efficient synthetic strategy to construct the linear homoallylic quinolone structures through the intermolecular addition of 2-alkynylquinoline to N-allenyl sulfonamides. We developed the regio- and diastereoselective transition metal-free hydroalkylation of 1,2-dienes by a structure containing a push-pull system. Moreover, the present work was carried out with a high atom economy, mild reaction conditions, and moderate to high yields. |
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| Beschreibung: | Gesehen am 09.12.2022 |
| Beschreibung: | Online Resource |
| ISSN: | 1477-0539 |
| DOI: | 10.1039/D2OB01362B |