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Harmonizing neuropsychological assessment for mild neurocognitive disorders in Europe

Introduction Harmonized neuropsychological assessment for neurocognitive disorders, an international priority for valid and reliable diagnostic procedures, has been achieved only in specific countries or research contexts. Methods To harmonize the assessment of mild cognitive impairment in Europe, a...

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Main Authors: Boccardi, Marina (Author) , Monsch, Andreas U. (Author) , Ferrari, Clarissa (Author) , Altomare, Daniele (Author) , Berres, Manfred (Author) , Bos, Isabelle (Author) , Buchmann, Andreas (Author) , Cerami, Chiara (Author) , Didic, Mira (Author) , Festari, Cristina (Author) , Nicolosi, Valentina (Author) , Sacco, Leonardo (Author) , Aerts, Liesbeth (Author) , Albanese, Emiliano (Author) , Annoni, Jean-Marie (Author) , Ballhausen, Nicola (Author) , Chicherio, Christian (Author) , Démonet, Jean-François (Author) , Descloux, Virginie (Author) , Diener, Suzie (Author) , Ferreira, Daniel (Author) , Georges, Jean (Author) , Gietl, Anton (Author) , Girtler, Nicola (Author) , Kilimann, Ingo (Author) , Klöppel, Stefan (Author) , Kustyniuk, Nicole (Author) , Mecocci, Patrizia (Author) , Mella, Nathalie (Author) , Pigliautile, Martina (Author) , Seeher, Katrin (Author) , Shirk, Steven D. (Author) , Toraldo, Alessio (Author) , Brioschi-Guevara, Andrea (Author) , Chan, Kwun C. G. (Author) , Crane, Paul K. (Author) , Dodich, Alessandra (Author) , Grazia, Alice (Author) , Kochan, Nicole A (Author) , de Oliveira, Fabricio Ferreira (Author) , Nobili, Flavio (Author) , Kukull, Walter (Author) , Peters, Oliver (Author) , Ramakers, Inez (Author) , Sachdev, Perminder S. (Author) , Teipel, Stefan (Author) , Visser, Pieter Jelle (Author) , Wagner, Michael (Author) , Weintraub, Sandra (Author) , Westman, Eric (Author) , Frölich, Lutz (Author) , Brodaty, Henry (Author) , Dubois, Bruno (Author) , Cappa, Stefano F. (Author) , Salmon, David (Author) , Winblad, Bengt (Author) , Frisoni, Giovanni B. (Author) , Kliegel, Matthias (Author)
Format: Article (Journal)
Language:English
Published: January 2022
In: Alzheimer's and dementia
Year: 2022, Volume: 18, Issue: 1, Pages: 29-42
ISSN:1552-5279
DOI:10.1002/alz.12365
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1002/alz.12365
Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/alz.12365
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Author Notes:Marina Boccardi, Andreas U. Monsch, Clarissa Ferrari, Daniele Altomare, Manfred Berres, Isabelle Bos, Andreas Buchmann, Chiara Cerami, Mira Didic, Cristina Festari, Valentina Nicolosi, Leonardo Sacco, Liesbeth Aerts, Emiliano Albanese, Jean-Marie Annoni, Nicola Ballhausen, Christian Chicherio, Jean-François Démonet, Virginie Descloux, Suzie Diener, Daniel Ferreira, Jean Georges, Anton Gietl, Nicola Girtler, Ingo Kilimann, Stefan Klöppel, Nicole Kustyniuk, Patrizia Mecocci, Nathalie Mella, Martina Pigliautile, Katrin Seeher, Steven D. Shirk, Alessio Toraldo, Andrea Brioschi-Guevara, Kwun C. G. Chan, Paul K. Crane, Alessandra Dodich, Alice Grazia, Nicole A Kochan, Fabricio Ferreira de Oliveira, Flavio Nobili, Walter Kukull, Oliver Peters, Inez Ramakers, Perminder S. Sachdev, Stefan Teipel, Pieter Jelle Visser, Michael Wagner, Sandra Weintraub, Eric Westman, Lutz Froelich, Henry Brodaty, Bruno Dubois, Stefano F. Cappa, David Salmon, Bengt Winblad, Giovanni B. Frisoni, Matthias Kliegel on behalf of the Consortium for the Harmonization of Neuropsychological Assessment for Neurocognitive Disorders
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Summary:Introduction Harmonized neuropsychological assessment for neurocognitive disorders, an international priority for valid and reliable diagnostic procedures, has been achieved only in specific countries or research contexts. Methods To harmonize the assessment of mild cognitive impairment in Europe, a workshop (Geneva, May 2018) convened stakeholders, methodologists, academic, and non-academic clinicians and experts from European, US, and Australian harmonization initiatives. Results With formal presentations and thematic working-groups we defined a standard battery consistent with the U.S. Uniform DataSet, version 3, and homogeneous methodology to obtain consistent normative data across tests and languages. Adaptations consist of including two tests specific to typical Alzheimer's disease and behavioral variant frontotemporal dementia. The methodology for harmonized normative data includes consensus definition of cognitively normal controls, classification of confounding factors (age, sex, and education), and calculation of minimum sample sizes. Discussion This expert consensus allows harmonizing the diagnosis of neurocognitive disorders across European countries and possibly beyond.
Item Description:Gesehen am 16.12.2022
Physical Description:Online Resource
ISSN:1552-5279
DOI:10.1002/alz.12365

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