Host genetic loci LZTFL1 and CCL2 associated with SARS-CoV-2 infection and severity of COVID-19

Host genetic factors contribute to the variable severity of COVID-19. We examined genetic variants from genome-wide association studies and candidate gene association studies in a cohort of patients with COVID-19 and investigated the role of early SARS-CoV-2 strains in COVID-19 severity.

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Main Authors: Rüter, Jule (Author) , Pallerla, Srinivas Reddy (Author) , Meyer, Christian G. (Author) , Casadei, Nicolas (Author) , Sonnabend, Michael (Author) , Peter, Silke (Author) , Nurjadi, Dennis (Author) , Linh, Le Thi Kieu (Author) , Fendel, Rolf (Author) , Göpel, Siri (Author) , Riess, Olaf (Author) , Kremsner, Peter G. (Author) , Velavan, Thirumalaisamy P. (Author)
Format: Article (Journal)
Language:English
Published: 23 June 2022
In: International journal of infectious diseases
Year: 2022, Volume: 122, Pages: 427-436
ISSN:1878-3511
DOI:10.1016/j.ijid.2022.06.030
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ijid.2022.06.030
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1201971222003654
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Author Notes:Jule Rüter, Srinivas Reddy Pallerla, Christian G. Meyer, Nicolas Casadei, Michael Sonnabend, Silke Peter, Dennis Nurjadi, Le Thi Kieu Linh, Rolf Fendel, Siri Göpel, Olaf Riess, Peter G. Kremsner, Thirumalaisamy P. Velavan
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Summary:Host genetic factors contribute to the variable severity of COVID-19. We examined genetic variants from genome-wide association studies and candidate gene association studies in a cohort of patients with COVID-19 and investigated the role of early SARS-CoV-2 strains in COVID-19 severity.
Item Description:Version des Artikels vom 5 July 2022
Gesehen am 20.12.2022
Physical Description:Online Resource
ISSN:1878-3511
DOI:10.1016/j.ijid.2022.06.030