Visualizing translation dynamics at atomic detail inside a bacterial cell
Translation is the fundamental process of protein synthesis and is catalysed by the ribosome in all living cells1. Here we use advances in cryo-electron tomography and sub-tomogram analysis2,3 to visualize the structural dynamics of translation inside the bacterium Mycoplasma pneumoniae.
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| Main Authors: | , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
28 September 2022
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| In: |
Nature
Year: 2022, Volume: 610, Issue: 7930, Pages: 205-211 |
| ISSN: | 1476-4687 |
| DOI: | 10.1038/s41586-022-05255-2 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1038/s41586-022-05255-2 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s41586-022-05255-2 |
| Author Notes: | Liang Xue, Swantje Lenz, Maria Zimmermann-Kogadeeva, Dimitry Tegunov, Patrick Cramer, Peer Bork, Juri Rappsilber & Julia Mahamid |
| Summary: | Translation is the fundamental process of protein synthesis and is catalysed by the ribosome in all living cells1. Here we use advances in cryo-electron tomography and sub-tomogram analysis2,3 to visualize the structural dynamics of translation inside the bacterium Mycoplasma pneumoniae. |
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| Item Description: | Gesehen am 20.12.2022 |
| Physical Description: | Online Resource |
| ISSN: | 1476-4687 |
| DOI: | 10.1038/s41586-022-05255-2 |