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Age-adjusted Charlson comorbidity index in recurrent glioblastoma: a new prognostic factor?

For recurrent glioblastoma (GB) patients, several therapy options have been established over the last years such as more aggressive surgery, re-irradiation or chemotherapy. Age and the Karnofsky Performance Status Scale (KPSS) are used to make decisions for these patients as these are established as...

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Main Authors: Barz, Melanie (Author) , Bette, Stefanie (Author) , Janssen, Insa (Author) , Aftahy, A. Kaywan (Author) , Huber, Thomas (Author) , Liesche-Starnecker, Friederike (Author) , Ryang, Yu-Mi (Author) , Wiestler, Benedikt (Author) , Combs, Stephanie (Author) , Meyer, Bernhard (Author) , Gempt, Jens (Author)
Format: Article (Journal)
Language:English
Published: 21 January 2022
In: BMC neurology
Year: 2022, Volume: 22, Pages: 1-8
ISSN:1471-2377
DOI:10.1186/s12883-021-02532-x
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12883-021-02532-x
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Author Notes:Melanie Barz, Stefanie Bette, Insa Janssen, A. Kaywan Aftahy, Thomas Huber, Friederike Liesche-Starnecker, Yu-Mi Ryang, Benedikt Wiestler, Stephanie E. Combs, Bernhard Meyer and Jens Gempt
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Summary:For recurrent glioblastoma (GB) patients, several therapy options have been established over the last years such as more aggressive surgery, re-irradiation or chemotherapy. Age and the Karnofsky Performance Status Scale (KPSS) are used to make decisions for these patients as these are established as prognostic factors in the initial diagnosis of GB. This study’s aim was to evaluate preoperative patient comorbidities by using the age-adjusted Charlson Comorbidity Index (ACCI) as a prognostic factor for recurrent GB patients.
Item Description:Gesehen am 31.01.2023
Physical Description:Online Resource
ISSN:1471-2377
DOI:10.1186/s12883-021-02532-x

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