Hysteroscopic findings in women with two and with more than two first-trimester miscarriages are not significantly different

The purpose of this study was to analyse hysteroscopic results in patients with recurrent miscarriages and to compare the frequency of uterine anomalies in women with a history of exactly two and with more than two consecutive miscarriages. A retrospective analysis of 206 patients undergoing hystero...

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Main Authors: Bohlmann, Michael K. (Author) , Wolff, Michael von (Author) , Luedders, Doerte W. (Author) , Beuter-Winkler, Petra (Author) , Diedrich, Klaus (Author) , Hornemann, Amadeus (Author) , Strowitzki, Thomas (Author)
Format: Article (Journal)
Language:English
Published: 24 April 2010
In: Reproductive biomedicine online
Year: 2010, Volume: 21, Issue: 2, Pages: 230-236
ISSN:1472-6491
DOI:10.1016/j.rbmo.2010.04.016
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.rbmo.2010.04.016
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1472648310002282
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Author Notes:Michael K Bohlmann, Michael von Wolff, Doerte W Luedders, Petra Beuter-Winkler, Klaus Diedrich, Amadeus Hornemann, Thomas Strowitzki
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Summary:The purpose of this study was to analyse hysteroscopic results in patients with recurrent miscarriages and to compare the frequency of uterine anomalies in women with a history of exactly two and with more than two consecutive miscarriages. A retrospective analysis of 206 patients undergoing hysteroscopy for repeated early pregnancy losses was performed at two university centres. Late miscarriages were excluded, terminations of pregnancy were not counted. Eighty-seven patients had suffered from exactly two early miscarriages and 119 from more than two. Both groups were comparable with respect to age at admission (32.95±4.46 versus 34.06±5.02years) and at first miscarriage (30.43±4.24 versus 29.08±5.38years). The prevalence of acquired (adhesions, polyps, fibroids) and congenital uterine anomalies (septate or bicornuate uterus, etc.) did not differ significantly (acquired: 28.7 versus 27.7%; congenital: 9.2 versus 16.8%). The rates of uterine anomalies did not differ significantly overall (36.8 versus 42.9%). In conclusion, uterine anomalies are frequently found in patients with two and with more than two early miscarriages. Due to the high rate of anomalies, their risk for adverse pregnancy outcome and a possible therapeutic approach, hysteroscopy might be a diagnostic option even after two early miscarriages.
Item Description:Gesehen am 02.02.2023
Physical Description:Online Resource
ISSN:1472-6491
DOI:10.1016/j.rbmo.2010.04.016