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Mechanical strength of antibiotic-loaded PMMA spacers in two-stage revision surgery

Antibiotic-loaded polymethylmethacrylate (PMMA) bone cement spacers provide high local antibiotic concentrations and patient mobility during the interim period of two-stage revision for periprosthetic joint infection (PJI). This study compares mechanical characteristics of six dual antibiotic-loaded...

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Hauptverfasser: Lunz, André (VerfasserIn) , Knappe, Kevin (VerfasserIn) , Omlor, Georg (VerfasserIn) , Schonhoff, Mareike (VerfasserIn) , Renkawitz, Tobias (VerfasserIn) , Jäger, Sebastian (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 29 October 2022
In: BMC musculoskeletal disorders
Year: 2022, Jahrgang: 23, Pages: 1-9
ISSN:1471-2474
DOI:10.1186/s12891-022-05895-5
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12891-022-05895-5
Volltext
Verfasserangaben:Andre Lunz, Kevin Knappe, Georg W. Omlor, Mareike Schonhoff, Tobias Renkawitz and Sebastian Jaeger
Beschreibung
Zusammenfassung:Antibiotic-loaded polymethylmethacrylate (PMMA) bone cement spacers provide high local antibiotic concentrations and patient mobility during the interim period of two-stage revision for periprosthetic joint infection (PJI). This study compares mechanical characteristics of six dual antibiotic-loaded bone cement (dALBC) preparations made from three different PMMA bone cements. The study`s main objective was to determine the effect of time and antibiotic concentration on mechanical strength of dALBCs frequently used for spacer fabrication in the setting of two-stage revision for PJI.
Beschreibung:Gesehen am 09.02.2023
Beschreibung:Online Resource
ISSN:1471-2474
DOI:10.1186/s12891-022-05895-5

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