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Mechanical strength of antibiotic-loaded PMMA spacers in two-stage revision surgery

Antibiotic-loaded polymethylmethacrylate (PMMA) bone cement spacers provide high local antibiotic concentrations and patient mobility during the interim period of two-stage revision for periprosthetic joint infection (PJI). This study compares mechanical characteristics of six dual antibiotic-loaded...

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Bibliographic Details
Main Authors: Lunz, André (Author) , Knappe, Kevin (Author) , Omlor, Georg (Author) , Schonhoff, Mareike (Author) , Renkawitz, Tobias (Author) , Jäger, Sebastian (Author)
Format: Article (Journal)
Language:English
Published: 29 October 2022
In: BMC musculoskeletal disorders
Year: 2022, Volume: 23, Pages: 1-9
ISSN:1471-2474
DOI:10.1186/s12891-022-05895-5
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12891-022-05895-5
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Author Notes:Andre Lunz, Kevin Knappe, Georg W. Omlor, Mareike Schonhoff, Tobias Renkawitz and Sebastian Jaeger
Description
Summary:Antibiotic-loaded polymethylmethacrylate (PMMA) bone cement spacers provide high local antibiotic concentrations and patient mobility during the interim period of two-stage revision for periprosthetic joint infection (PJI). This study compares mechanical characteristics of six dual antibiotic-loaded bone cement (dALBC) preparations made from three different PMMA bone cements. The study`s main objective was to determine the effect of time and antibiotic concentration on mechanical strength of dALBCs frequently used for spacer fabrication in the setting of two-stage revision for PJI.
Item Description:Gesehen am 09.02.2023
Physical Description:Online Resource
ISSN:1471-2474
DOI:10.1186/s12891-022-05895-5

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