Anaesthesia as an influence in tumour progression
Tumour growth and the formation of metastases are essential elements in the progression of cancer. The centre of treatment is the surgical resection of primary solid tumours. But even if the tumour can be removed without microscopic residual cells, local recurrences and distant metastases occur and...
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| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
01 February 2021
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| In: |
Langenbeck's archives of surgery
Year: 2021, Jahrgang: 406, Heft: 5, Pages: 1283-1294 |
| ISSN: | 1435-2451 |
| DOI: | 10.1007/s00423-021-02078-z |
| Online-Zugang: | Resolving-System, kostenfrei, Volltext: https://doi.org/10.1007/s00423-021-02078-z
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| Verfasserangaben: | Jadie Plücker, Naita M. Wirsik, Alina S. Ritter, Thomas Schmidt, Markus A. Weigand |
| Zusammenfassung: | Tumour growth and the formation of metastases are essential elements in the progression of cancer. The centre of treatment is the surgical resection of primary solid tumours. But even if the tumour can be removed without microscopic residual cells, local recurrences and distant metastases occur and determine the patient’s fate. During the operation, tumour cells are shed from the primary tumour and released into the circulation. These circulating tumour cells might play an important role in the formation of new tumour sites. Therefore, a functional innate and adaptive immune system is essential, especially in this perioperative period. Anaesthesia influences consciousness and pain perception and interacts directly with the immune system and tumour cells. |
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| Beschreibung: | Gesehen am 21.02.2023 |
| Beschreibung: | Online Resource |
| ISSN: | 1435-2451 |
| DOI: | 10.1007/s00423-021-02078-z |