Biological variation of high sensitive Troponin T in stable heart failure patients with ischemic or dilated cardiomyopathy

High sensitive Troponin (hsTn) assays enable detection of minimal marker elevation in heart failure patients previously deemed Troponin negative. Biovariability, reference change values (RCV), and index of individuality (II) have not been previously described for hsTnT although serial testing is imp...

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Main Authors: Frankenstein, Lutz (Author) , Remppis, Bjoern-Andrew (Author) , Giannitsis, Evangelos (Author) , Frankenstein, Joerdis (Author) , Hess, Georg (Author) , Zdunek, Dietmar (Author) , Dösch, Andreas (Author) , Zugck, Christian (Author) , Katus, Hugo (Author)
Format: Article (Journal)
Language:English
Published: 17. Februar 2011
In: Clinical research in cardiology
Year: 2011, Volume: 100, Issue: 8, Pages: 633-640
ISSN:1861-0692
DOI:10.1007/s00392-011-0285-4
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00392-011-0285-4
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Author Notes:Lutz Frankenstein, Andrew Remppis, Evangelos Giannitis, Joerdis Frankenstein, Georg Hess, Dietmar Zdunek, Andreas Doesch, Christian Zugck, Hugo A. Katus
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Summary:High sensitive Troponin (hsTn) assays enable detection of minimal marker elevation in heart failure patients previously deemed Troponin negative. Biovariability, reference change values (RCV), and index of individuality (II) have not been previously described for hsTnT although serial testing is important in interpreting low concentrations. For these values, a difference between ischemic heart disease (IHD) and dilated cardiomyopathy (dCMP) appears conceivable.
Item Description:Gesehen am 27.02.2023
Physical Description:Online Resource
ISSN:1861-0692
DOI:10.1007/s00392-011-0285-4