Platelets contribute to postnatal occlusion of the ductus arteriosus

Premature infants can suffer from an anatomical defect in which the ductus arteriosus, a blood vessel that connects the pulmonary artery and the aorta during fetal development, fails to close at birth. Katrin Echtler et al. now show that platelets are needed for closure in mice and that reduced plat...

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Bibliographic Details

Main Authors:	Echtler, Katrin (Author) , Stark, Konstantin (Author) , Lorenz, Michael (Author) , Kerstan, Sandra (Author) , Walch, Axel (Author) , Jennen, Luise (Author) , Rudelius, Martina (Author) , Seidl, Stefan (Author) , Kremmer, Elisabeth (Author) , Emambokus, Nikla R. (Author) , von Bruehl, Marie-Luise (Author) , Frampton, Jon (Author) , Isermann, Berend (Author) , Genzel-Boroviczény, Orsolya (Author) , Schreiber, Christian (Author) , Mehilli, Julinda (Author) , Kastrati, Adnan (Author) , Schwaiger, Markus (Author) , Shivdasani, Ramesh A. (Author) , Massberg, Steffen (Author)
Format:	Article (Journal)
Language:	English
Published:	2010
In:	Nature medicine Year: 2010, Volume: 16, Issue: 1, Pages: 75-82
ISSN:	1546-170X
DOI:	10.1038/nm.2060
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/nm.2060 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/nm.2060
Author Notes:	Katrin Echtler, Konstantin Stark, Michael Lorenz, Sandra Kerstan, Axel Walch, Luise Jennen, Martina Rudelius, Stefan Seidl, Elisabeth Kremmer, Nikla R. Emambokus, Marie-Luise von Bruehl, Jon Frampton, Berend Isermann, Orsolya Genzel-Boroviczény, Christian Schreiber, Julinda Mehilli, Adnan Kastrati, Markus Schwaiger, Ramesh A. Shivdasani & Steffen Massberg