A cellular view of Nf2 in liver homeostasis and tumorigenesis

How liver adjusts and stabilizes its size is unsolved so far; the answers to this question may also provide insights into mechanisms of hepatocarcinogenesis. Two recent papers suggest a role for Merlin/Nf2 in control of liver cell turnover, but results appear conflicting at first glance.

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Bibliographic Details
Main Authors: Breuhahn, Kai (Author) , Schirmacher, Peter (Author)
Format: Article (Journal) Editorial
Language:English
Published: 14 September 2010
In: Developmental cell
Year: 2010, Volume: 19, Issue: 3, Pages: 363-364
ISSN:1878-1551
DOI:10.1016/j.devcel.2010.08.015
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.devcel.2010.08.015
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1534580710003904
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Author Notes:Kai Breuhahn and Peter Schirmacher
Description
Summary:How liver adjusts and stabilizes its size is unsolved so far; the answers to this question may also provide insights into mechanisms of hepatocarcinogenesis. Two recent papers suggest a role for Merlin/Nf2 in control of liver cell turnover, but results appear conflicting at first glance.
Item Description:Gesehen am 01.03.2023
Physical Description:Online Resource
ISSN:1878-1551
DOI:10.1016/j.devcel.2010.08.015