Synergistic effect of cinacalcet and active vitamin D in a dialysis patient with secondary hyperparathyroidism

While treating a long-term dialysis patient for secondary hyperparathyroidism (SHPT), indications of a synergistic effect between cinacalcet HCl and active vitamin D were observed. After 2.5 years, high initial cinacalcet doses of 180 mg/day could be significantly reduced to only 30 mg/non-dialysis...

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Hauptverfasser: Karger, Christian (VerfasserIn) , Schwenger, Vedat (VerfasserIn) , Sommerer, Claudia (VerfasserIn) , Zeier, Martin (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 25 February 2010
In: Dialysis & transplantation
Year: 2010, Jahrgang: 39, Heft: 2, Pages: 69-71
ISSN:1932-6920
DOI:10.1002/dat.20405
Online-Zugang:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1002/dat.20405
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/dat.20405
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Verfasserangaben:Christian P. Karger, Vedat Schwenger, Claudia Sommerer, Martin Zeier
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Zusammenfassung:While treating a long-term dialysis patient for secondary hyperparathyroidism (SHPT), indications of a synergistic effect between cinacalcet HCl and active vitamin D were observed. After 2.5 years, high initial cinacalcet doses of 180 mg/day could be significantly reduced to only 30 mg/non-dialysis day without losing control over the intact parathyroid hormone. Calcium-phosphorus product improved over time. The combination of cinacalcet and active vitamin D may improve the treatment of SHPT in dialysis patients.
Beschreibung:Gesehen am 02.03.2023
Beschreibung:Online Resource
ISSN:1932-6920
DOI:10.1002/dat.20405